Comparison of methods for searching protein sequence databases
نویسندگان
چکیده
منابع مشابه
Comparison of methods for searching protein sequence databases.
We have compared commonly used sequence comparison algorithms, scoring matrices, and gap penalties using a method that identifies statistically significant differences in performance. Search sensitivity with either the Smith-Waterman algorithm or FASTA is significantly improved by using modern scoring matrices, such as BLOSUM45-55, and optimized gap penalties instead of the conventional PAM250 ...
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ژورنال
عنوان ژورنال: Protein Science
سال: 1995
ISSN: 0961-8368
DOI: 10.1002/pro.5560040613